[기본개념] 시퀀싱 파일이름 의미!

 NCBI에서 유전자들을 찾아볼 때, Reference Sequence를 확인할 수가 있다.

 

여기서 Reference sequencing을 보게되면 NM_머시기라고 되어있는것을 확인할 수가 있다.

 

 

가끔 NM말고도 다른 prefix를 보인는데 다음과 같이 정리하였다.

Accession Prefix	Molecule type	Comment
AC_	Genomic	Complete genomic molecule, usually alternate assembly
NC_	Genomic	Complete genomic molecule, usually alternate assembly
NG_	Genomic	Incomplete genomic region
NT_	Genomic	Contig or scaffold, clone-based or WGS (Whole Genome Shotgun sequence data)
NW_	Genomic	Contig or scaffold, primarily WGS (Whole Genome Shotgun sequence data)
NZ_	Genomic	Complete genomes and unfinished WGS data
NM_	mRNA	Protein-coding transcripts (usually curated)
NR_	RNA	Non-protein-coding transcripts
XM_	mRNA	predicted model protein-coding transcript
XR_	RNA	Predicted model non-protein-coding transcript
AP_	Protein	Annotated on AC_alternate assembly
NP_	Protein	Associated with an NM_ or NC_ accession
YP_	Protein	Annotated on genomic molecules without an instantiated transcript recode
XP_	Protein	Predicted model, associated with an XM_accession
WP_	Protein	Non-redundant across multiple strains and species

 

출처 : ncbi.nlm.nih.gov/books/NBK21091/table/ch18.T.refseq_accession_numbers_and_mole/

Table 1. [RefSeq accession numbers and molecule types.]. - The NCBI Handbook - NCBI Bookshelf